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Anti-MSH2 Monoclonal Antibody

Boster Bio Anti-MSH2 Monoclonal Antibody catalog # M00140. Tested in WB, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Matrix metalloproteinase-9; MMP-9;3.4.24.35;92 kDa gelatinase;92 kDa type IV collagenase; Gelatinase B; GELB;67 kDa matrix metalloproteinase-9;82 kDa matrix metalloproteinase-9; MMP9; CLG4B

Gene Name

Matrix metalloproteinase-9

UniProt

P43246

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human MSH2 MSH2 (MutS homologue 2) forms the hMutS- Alpha dimer with MSH6 and is an essential component of the mismatch repair process. hMutS- Alpha is part of the BRCA1-associated surveillance complex (BASC), a complex that also contains BRCA1, MLH1, ATM, BLM, PMS2 proteins and the Rad50-Mre11-NBS1 complex.

Clonality

Monoclonal

Clone

Clone: ACIH-13

Tissue Specificity

Produced by normal alveolar macrophages and granulocytes.

Applications

WB, Flow Cytometry

Field of Research

Cancer, DNA/RNA, DNA Damage & Repair, Epigenetics and Nuclear Signaling, Oncoproteins/Suppressors, Tumor Suppressors

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00140

Product MSDS

https://www.bosterbio.com/msds?sku=M00140

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>FC 1:50

Other Gene Names

MSH2

Subcellular Location

Secreted, extracellular space, extracellular matrix .

Protein Name

P2X purinoceptor 1

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