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Anti-Bcl-2 Rabbit Monoclonal Antibody

Boster Bio Anti-Bcl-2

Product Specifications

Synonyms

Apoptosis regulator Bcl-2; BCL2

Gene Name

Apoptosis regulator Bcl-2

UniProt

P10415

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human Bcl-2

Clonality

Monoclonal

Clone

Clone: AAOH-2

Tissue Specificity

Expressed in a variety of tissues.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Apoptosis, Apoptotic Markers, Cancer, Cancer Metabolism, Cell Biology, Cell Death, Hypoxia, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Oncoproteins, Oncoproteins/Suppressors, Pathways and Processes, Response To Hypoxia, Signal Transduction, Tumor Biomarkers

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00040-2

Product MSDS

https://www.bosterbio.com/msds?sku=M00040-2

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>FC 1:50

Other Gene Names

BCL2

Subcellular Location

Mitochondrion outer membrane ; Single-pass membrane protein . Nucleus membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein .

Protein Name

P2X purinoceptor 1

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