Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Apolipoprotein E APOE Monoclonal Antibody

Boster Bio Anti-Apolipoprotein E APOE Monoclonal Antibody catalog # M00015. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF

Gene Name

Signal transducer and activator of transcription 3

UniProt

P02649

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human Apolipoprotein E

Clonality

Monoclonal

Clone

Clone: AbA15

Tissue Specificity

Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Applications

WB, IHC, ICC, IF, IP

Field of Research

Cardiovascular, Lipid Metabolism, Lipids/Lipoproteins, Metabolism, Signal Transduction

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6) - responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00015

Product MSDS

https://www.bosterbio.com/msds?sku=M00015

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>IP 1:50

Other Gene Names

APOE

Subcellular Location

Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3. Identified in a complex with LYN and PAG1.

Protein Name

P2X purinoceptor 1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RNF2 Antibody - middle region
MBS3219220-01 0.1 mL

RNF2 Antibody - middle region

Ask
View Details
RNF2 Antibody - middle region
MBS3219220-02 5x 0.1 mL

RNF2 Antibody - middle region

Ask
View Details
HSD17B1 Rabbit Polyclonal Antibody
E10G04948 100 μl

HSD17B1 Rabbit Polyclonal Antibody

Ask
View Details
WDR61 Rabbit pAb
E45R22087N 50 ul

WDR61 Rabbit pAb

Ask
View Details
Anti-CD74(CLIP/1133), CF488A conjugate
BNC881133-500 500 µL

Anti-CD74(CLIP/1133), CF488A conjugate

Ask
View Details
F(ab')2 Sheep IgG (H&L) Antibody Texas Red™ Conjugated
TA398247 500 µL

F(ab')2 Sheep IgG (H&L) Antibody Texas Red™ Conjugated

Ask
View Details