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Anti-RDM1 Antibody

Boster Bio Anti-RDM1 Antibody (Catalog # A10968) . Tested in IHC applications. This antibody reacts with Human.

Product Specifications

Background

May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA.<br><br>Hamimes S., J. Biol. Chem. 280:9225-9235(2005).<br>Messaoudi L., Nucleic Acids Res. 35:6571-6587(2007).<br>Zody M.C., Nature 440:1045-1049(2006).

Synonyms

RAD52 motif-containing protein 1; RAD52 homolog B; RDM1; RAD52B

Gene Name

RDM1

UniProt

Q8NG50

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human RDM1.

Clonality

Polyclonal

Tissue Specificity

Expressed in testis. .

Applications

IHC

Field of Research

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Immunohistochemistry: 1:50~1:100

Form

Liquid

Function

May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. .

Molecular Weight

31970 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A10968

Product MSDS

https://www.bosterbio.com/msds?sku=A10968

Other Gene Names

RAD52 motif-containing protein 1

Subcellular Location

Nucleus . Cytoplasm . Nucleus, nucleolus . Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and isoform 10 are relocalized to the nucleolus as dot-like or irregular subnuclear structures. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB) ; this association with nuclear bodies is enhanced in response to proteotoxic stress. Isoform 3, but not isoform 1 and isoform 5, is relocalized in nucleolar caps during transcriptional arrest.
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