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Anti-DUS2/Dus2LL Antibody

Boster Bio Anti-DUS2/Dus2LL Antibody (Catalog # A10393) . Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.<br><br>Ota T., Nat. Genet. 36:40-45(2004).<br>The MGC Project Team; Genome Res. 14:2121-2127(2004).<br>Kato T., Cancer Res. 65:5638-5646(2005).

Synonyms

TRNA-dihydrouridine (20) synthase [NAD (P) +]-like;1.3.1.-; Dihydrouridine synthase 2; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2; DUS2; DUS2L

Gene Name

DUS2

UniProt

Q9NX74

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from C-terminal of human DUS2L.

Clonality

Polyclonal

Tissue Specificity

Weak expression in heart, placenta and skeletal muscle. Up-regulated in most lung cancer cells (at protein level) . .

Applications

WB, IHC

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing, Translation

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR. .

Molecular Weight

55050 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A10393

Product MSDS

https://www.bosterbio.com/msds?sku=A10393

Other Gene Names

TRNA-dihydrouridine (20) synthase [NAD (P) +]-like

Subcellular Location

Cytoplasm . Endoplasmic reticulum . Mainly at the endoplasmic reticulum.

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