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Anti-SCN7A Antibody

Boster Bio Anti-SCN7A Antibody (Catalog # A09448) . Tested in IF applications. This antibody reacts with Human.

Product Specifications

Background

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.<br><br>George A.L. Jr., Proc. Natl. Acad. Sci. U.S.A. 89:4893-4897(1992).

Synonyms

Sodium channel protein type 7 subunit alpha; Putative voltage-gated sodium channel subunit alpha Nax; Sodium channel protein cardiac and skeletal muscle subunit alpha; Sodium channel protein type VII subunit alpha; SCN7A; SCN6A

Gene Name

SCN7A

UniProt

Q01118

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human SCN7A.

Clonality

Polyclonal

Tissue Specificity

Heart and uterus. .

Applications

IF

Field of Research

Neuroscience, Neurotransmission, Receptors / Channels

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Immunofluorescence: 1:100~1:500

Form

Liquid

Function

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na (+) ions may pass in accordance with their electrochemical gradient. .

Molecular Weight

193493 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A09448

Product MSDS

https://www.bosterbio.com/msds?sku=A09448

Other Gene Names

Sodium channel protein type 7 subunit alpha

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

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