Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-CHP2 Antibody

Boster Bio Anti-CHP2 Antibody (Catalog # A08478) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.<br><br>Loftus B.J., Genomics 60:295-308(1999).<br>Wang Y., J. Immunol. 169:1102-1109(2002).<br>Pang T., J. Biol. Chem. 277:43771-43777(2002).

Synonyms

Calcineurin B homologous protein 2; Hepatocellular carcinoma-associated antigen 520; CHP2; HCA520

Gene Name

CHP2

UniProt

O43745

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of humanCHP2.

Clonality

Polyclonal

Tissue Specificity

Expressed in malignantly transformed cells but not detected in normal tissues. .

Applications

WB

Field of Research

Calcium Binding Proteins, Calcium Signaling, Signal Transduction, Signaling Pathway

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na (+) /H (+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation- induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus. .

Molecular Weight

22452 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A08478

Product MSDS

https://www.bosterbio.com/msds?sku=A08478

Other Gene Names

Calcineurin B homologous protein 2

Subcellular Location

Nucleus . Cytoplasm . Cell membrane . Predominantly localized in a juxtanuclear region. Colocalizes with SLC9A3 in the juxtanuclear region and at the plasma membrane (By similarity) . Exported from the nucleus to the cytoplasm through a nuclear export signal (NES) pathway. May shuttle between nucleus and cytoplasm. .
Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SAV1 (Protein Salvador Homolog 1, SAV, 45kD WW Domain Protein, WW45, hWW45, WWP4) (PE)
MBS6160125-01 0.1 mL

SAV1 (Protein Salvador Homolog 1, SAV, 45kD WW Domain Protein, WW45, hWW45, WWP4) (PE)

Ask
View Details
SAV1 (Protein Salvador Homolog 1, SAV, 45kD WW Domain Protein, WW45, hWW45, WWP4) (PE)
MBS6160125-02 5x 0.1 mL

SAV1 (Protein Salvador Homolog 1, SAV, 45kD WW Domain Protein, WW45, hWW45, WWP4) (PE)

Ask
View Details
RGD1561552 siRNA Oligos set (Rat)
39252176 3 x 5 nmol

RGD1561552 siRNA Oligos set (Rat)

Ask
View Details
TLR3 Polyclonal Antibody
E911778 100ul

TLR3 Polyclonal Antibody

Ask
View Details
FastScan™ LbCpf1 (Strain ND2006) /Cas12a ELISA Kit
CST 88197C 1 Kit

FastScan™ LbCpf1 (Strain ND2006) /Cas12a ELISA Kit

Ask
View Details