Anti-ARHGAP18 Antibody
Boster Bio Anti-ARHGAP18 Antibody catalog # A08418. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Rho GTPase-activating protein 18; MacGAP ; Rho-type GTPase-activating protein 18; ARHGAP18
Gene Name
ARHGAP18
UniProt
Q8N392
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human RHG18. AA range:517-566
Applications
WB
Purification
Immunogen affinity purified
Dilution
WB, 1:500-1:2000
Form
Liquid
Function
Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595) . Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702) . Regulates cell shape, spreading, and migration (PubMed:21865595) . .
Molecular Weight
74977 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A08418
Product MSDS
https://www.bosterbio.com/msds?sku=A08418
Fragment
IgG
Other Gene Names
Rho GTPase-activating protein 18
Subcellular Location
Cytoplasm .
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
QY-E05850 96 Tests
Human Anti-Alpha melanocyte stimulating hormone antibody (Anti-α-MSH antibody) ELISA Kit
Ask
View Details