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Anti-p140Cap SRCIN1 Antibody

Boster Bio Anti-p140Cap SRCIN1 Antibody catalog # A08110. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

SRC kinase signaling inhibitor 1; SNAP-25-interacting protein; SNIP; p130Cas-associated protein; p140Cap; SRCIN1; KIAA1684, P140

Gene Name

SRCIN1

UniProt

Q9C0H9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human SNIP. AA range:811-860

Tissue Specificity

Expressed in some primary breast carcinomas where its presence is significantly associated with increased tumor size. Not detected in normal breast tissue. .

Applications

WB

Purification

Immunogen affinity purified

Form

Liquid

Function

Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance. .

Molecular Weight

112453 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A08110

Product MSDS

https://www.bosterbio.com/msds?sku=A08110

Fragment

IgG

Other Gene Names

SRC kinase signaling inhibitor 1

Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, axon . Cell projection, dendrite . Cell junction, synapse . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions. Strongly expressed in axons and dendrites of the CA1 and CA3 hippocampal regions and of the dentate gyrus. Detected in both presynapses and postsynapses and in postsynaptic density fractions.
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