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Anti-Chondroitin sulfate synthase 1 CHSY1 Antibody

Boster Bio Anti-Chondroitin sulfate synthase 1 CHSY1 Antibody (Catalog # A07580) . Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Background

Has both beta-1, 3-glucuronic acid and beta-1, 4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.<br><br>Kitagawa H., J. Biol. Chem. 276:38721-38726(2001).<br>Nagase T., DNA Res. 6:63-70(1999).<br>Clark H.F., Genome Res. 13:2265-2270(2003).

Synonyms

Chondroitin sulfate synthase 1;2.4.1.175;2.4.1.226; Chondroitin glucuronyltransferase 1; Chondroitin synthase 1; ChSy-1; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; N-acetylgalactosaminyltransferase 1; CHSY1; CHSY, CSS1, KIAA0990; UNQ756/PRO1487

Gene Name

CHSY1

UniProt

Q86X52

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human CHSY1.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes. .

Applications

WB, IHC

Field of Research

Organelles, Subcellular Markers, Tags & Cell Markers

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling. .

Molecular Weight

91784 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07580

Product MSDS

https://www.bosterbio.com/msds?sku=A07580

Other Gene Names

Chondroitin sulfate synthase 1

Subcellular Location

Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Secreted .

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