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Anti-IRX3 Antibody

Boster Bio Anti-IRX3 Antibody (Catalog # A07258) . Tested in IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells By similarity.<br><br>Hansen L., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.<br>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br>Lewis M.T., Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.

Synonyms

Iroquois-class homeodomain protein IRX-3; Homeodomain protein IRXB1; Iroquois homeobox protein 3; IRX3; IRXB1

Gene Name

IRX3

UniProt

P78415

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from internal of human IRX3.

Clonality

Polyclonal

Applications

IHC

Field of Research

Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Epigenetics and Nuclear Signaling, Neurogenesis, Neurology Process, Neuroscience, Oncoproteins, Oncoproteins/Suppressors, Transcription, Transcription Factors

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Immunohistochemistry: 1:50~1:100

Form

Liquid

Function

Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity) . .

Molecular Weight

52119 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07258

Product MSDS

https://www.bosterbio.com/msds?sku=A07258

Other Gene Names

Iroquois-class homeodomain protein IRX-3

Subcellular Location

Nucleus .

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