Anti-BCAS3 Antibody
Boster Bio Anti-BCAS3 Antibody catalog # A07120. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Breast carcinoma-amplified sequence 3 ; GAOB1; BCAS3
Gene Name
BCAS3
UniProt
Q9H6U6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from BCAS3 . at AA range: 660-740
Tissue Specificity
Expressed in stomach, liver, lung, kidney, prostate, testis, thyroid gland, adrenal gland, brain, heart, skeletal muscle, colon, spleen, small intestine, placenta, blood leukocyte and mammary epithelial cells. Expressed in undifferentiated ES cells. Expressed in blood islands and nascent blood vessels derived from differentiated ES cells into embryoid bodies (BD) . Expressed in endothelial cells. Not detected in brain. Expressed in brain tumors (at protein level) . Expressed in brain. Highly expressed in breast cancers and in glioma cell lines. .
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity) . Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. .
Molecular Weight
101237 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A07120
Product MSDS
https://www.bosterbio.com/msds?sku=A07120
Fragment
IgG
Other Gene Names
Breast carcinoma-amplified sequence 3
Subcellular Location
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Localizes in the cytoplasm in stationary cells. Translocates from the cytoplasm to the leading edge in motile cells. Colocalizes with microtubules and intermediate filaments in both stationary and motile cells (By similarity) . Associates with chromatin. Recruited to estrogen receptor-induced promoters in a PELP1-dependent manner. .
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