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Anti-Sodium channel subunit beta-2 SCN2B Antibody

Boster Bio Anti-Sodium channel subunit beta-2 SCN2B Antibody (Catalog # A06842) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier By similarity.<br><br>Eubanks J., NeuroReport 8:2775-2779(1997).<br>Bolino A., Eur. J. Hum. Genet. 6:629-634(1998).<br>Cruz J.S., Science 284:711-711(1999).

Synonyms

Sodium channel subunit beta-2; SCN2B; UNQ326/PRO386

Gene Name

SCN2B

UniProt

O60939

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human SCN2B.

Clonality

Polyclonal

Tissue Specificity

Brain specific.

Applications

WB

Field of Research

Neuroscience, Neurotransmission, Receptors / Channels

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity) . .

Molecular Weight

24326 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06842

Product MSDS

https://www.bosterbio.com/msds?sku=A06842

Other Gene Names

Sodium channel subunit beta-2

Subcellular Location

Membrane; Single-pass type I membrane protein.

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