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Anti-IL11RA Antibody

Boster Bio Anti-IL11RA Antibody (Catalog # A06426) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.<br><br>Cherel M., Blood 86:2534-2540(1995).<br>Van Leuven F., Genomics 31:65-70(1996).<br>Kalnine N., Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.

Synonyms

Interleukin-11 receptor subunit alpha; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA; IL11RA

Gene Name

IL11RA

UniProt

Q14626

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from C-terminal of human IL11RA.

Clonality

Polyclonal

Tissue Specificity

Expressed in a number of cell lines, including the myelogenous leukemia cell line K-562, the megakaryocytic leukemia cell line M-07e, the erythroleukemia cell line TF-1, and the osteosarcoma cell lines, MG-63 and SaOS-2. Also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma. .

Applications

WB

Field of Research

Cancer, Cytokines, Hematopoietic Progenitors, Immunology, Innate Immunity, Interleukins, Receptors, Stem Cells, Surface Molecules, Tumor Biomarkers

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number. .

Molecular Weight

45222 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06426

Product MSDS

https://www.bosterbio.com/msds?sku=A06426

Other Gene Names

Interleukin-11 receptor subunit alpha

Subcellular Location

Membrane; Single-pass type I membrane protein.

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