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Anti-Myt 1 PKMYT1 Antibody

Boster Bio Anti-Myt 1 PKMYT1 Antibody catalog # A06247. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase;2.7.11.1; Myt1 kinase; PKMYT1; MYT1

Gene Name

PKMYT1

UniProt

Q99640

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human PKMYT1. AA range:49-98

Applications

WB

Purification

Immunogen affinity purified

Dilution

WB, 1:500-1:2000

Form

Liquid

Function

Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development. .

Molecular Weight

54521 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06247

Product MSDS

https://www.bosterbio.com/msds?sku=A06247

Fragment

IgG

Other Gene Names

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

Subcellular Location

Endoplasmic reticulum membrane ; Peripheral membrane protein . Golgi apparatus membrane ; Peripheral membrane protein .

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