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Anti-GluR6 GRM6 Antibody

Boster Bio Anti-GluR6 GRM6 Antibody (Catalog # A06163) . Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity By similarity. Signaling stimulates TRPM1 channel activity and Ca2+ uptake. Required for normal vision.<br><br>Inga Everts, J. Neurosci., Feb 1999; 19: 916.<br>Gregory D. Salinas, J. Biol. Chem., Dec 2006; 281: 40164 - 40173.<br>Sheng Yan, J. Neurosci., Jan 2004; 24: 679.<br>Xiao-Mei Liu, J. Biol. Chem., Jun 2006; 281: 17432 - 17445.

Synonyms

Metabotropic glutamate receptor 6; mGluR6; GRM6; GPRC1F, MGLUR6

Gene Name

GRM6

UniProt

O15303

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human GluR6.

Clonality

Polyclonal

Tissue Specificity

Detected in melanocytes. .

Applications

WB, IHC

Field of Research

Amino Acids, G Protein Signaling, Neuroscience, Neurotransmission, Neurotransmitter, Receptors / Channels, Signal Transduction, Signaling Pathway

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity) . Signaling stimulates TRPM1 channel activity and Ca (2+) uptake. Required for normal vision. .

Molecular Weight

95468 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06163

Product MSDS

https://www.bosterbio.com/msds?sku=A06163

Other Gene Names

Metabotropic glutamate receptor 6

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Cell projection, dendrite . Subject to trafficking from the endoplasmic reticulum to the Golgi apparatus and then to the cell membrane.
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