Anti-EHHADH Antibody

The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene.<br><br>Hoefler G., Genomics 19:60-67(1994).<br>Cherkaoui-Malki M., Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.<br>Totoki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

Peroxisomal bifunctional enzyme; PBE; PBFE; Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase;4.2.1.17;5.3.3.8;3-hydroxyacyl-CoA dehydrogenase;1.1.1.35; EHHADH; ECHD

Cancer, Cancer Metabolism, Cardiovascular, Fatty Acid Oxidation, Fatty Acids, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism of Lipids and Lipoproteins, Pathways and Processes, Redox Metabolism, Signal Transduction