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Anti-Cytochrome P450 3A7 CYP3A7 Antibody

Boster Bio Anti-Cytochrome P450 3A7 CYP3A7 Antibody (Catalog # A05417) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3AP1 pseudogene and is represented by GeneID:100861540.<br><br>Komori M., J. Biochem. 105:161-163(1989).<br>Gellner K., Pharmacogenetics 11:111-121(2001).<br>Scherer S.W., Science 300:767-772(2003).

Synonyms

Cytochrome P450 3A7;1.14.14.1; CYPIIIA7; Cytochrome P450-HFLA; CYP3A7

Gene Name

CYP3A7

UniProt

A4D288

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human Cytochrome P450 3A7.

Clonality

Polyclonal

Applications

WB

Field of Research

Cancer, Cardiovascular, Cytochromes, Drug Metabolism, Growth Factors/Hormones, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathways, Metabolism, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Molecular Weight

57526 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A05417

Product MSDS

https://www.bosterbio.com/msds?sku=A05417

Other Gene Names

Cytochrome P450 3A7

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

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