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Anti-MARK3 Antibody

Boster Bio Anti-MARK3 Antibody (Catalog # A05355) . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.<br><br>Peng C.Y., Cell Growth Differ. 9:197-208(1998).<br>Sun T.-Q., Nat. Cell Biol. 3:628-636(2001).<br>Wissing J., Mol. Cell. Proteomics 6:537-547(2007)

Synonyms

MAP/microtubule affinity-regulating kinase 3;2.7.11.1; C-TAK1; cTAK1; Cdc25C-associated protein kinase 1; ELKL motif kinase 2; EMK-2; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Par-1a; Serine/threonine-protein kinase p78; MARK3; CTAK1, EMK2

Gene Name

MARK3

UniProt

P27448

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from N-terminal of human MARK3.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, IHC

Field of Research

Cytoskeleton, Cytoskeleton/ECM, Microtubules, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Involved in the specific phosphorylation of microtubule- associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. .

Molecular Weight

84489 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A05355

Product MSDS

https://www.bosterbio.com/msds?sku=A05355

Other Gene Names

MAP/microtubule affinity-regulating kinase 3

Subcellular Location

Cell membrane ; Peripheral membrane protein .

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