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Anti-AChR alpha9 CHRNA9 Antibody

Boster Bio Anti-AChR alpha9 CHRNA9 Antibody catalog # A05280. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Neuronal acetylcholine receptor subunit alpha-9; Nicotinic acetylcholine receptor subunit alpha-9; NACHR alpha-9; CHRNA9; NACHRA9

Gene Name

CHRNA9

UniProt

Q9UGM1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the N-terminal region of human CHRNA9. AA range:50-100

Tissue Specificity

Expressed in cochlea, keratinocytes, pituitary gland, B-cells and T-cells. .

Applications

WB

Purification

Immunogen affinity purified

Form

Liquid

Function

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed:11752216, PubMed:25282151) . The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed:11752216, PubMed:25282151) . In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion (PubMed:11021840) . .

Molecular Weight

54807 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A05280

Product MSDS

https://www.bosterbio.com/msds?sku=A05280

Fragment

IgG

Other Gene Names

Neuronal acetylcholine receptor subunit alpha-9

Subcellular Location

Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .

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