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Anti-LFNG/Lunatic Fringe Antibody

Boster Bio Anti-LFNG/Lunatic Fringe Antibody (Catalog # A04513) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning By similarity.<br><br>Johnston S.H., Development 124:2245-2254(1997).<br>Cole S.E., Dev. Cell 3:75-84(2002).<br>Shimizu K., J. Biol. Chem. 276:25753-25758(2001)

Synonyms

Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe;2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; LFNG

Gene Name

LFNG

UniProt

Q8NES3

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human LFNG.

Clonality

Polyclonal

Applications

WB

Field of Research

Cytoplasmic, Developmental Biology, Embryogenesis, Neurogenesis, Neurology Process, Neuroscience, Signaling Pathways, Stem Cells

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity) . .

Molecular Weight

41773 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04513

Product MSDS

https://www.bosterbio.com/msds?sku=A04513

Other Gene Names

Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

Subcellular Location

Golgi apparatus membrane ; Single-pass type II membrane protein .

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