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Anti-ID4 Antibody

Boster Bio Anti-ID4 Antibody (Catalog # A03975) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding.<br><br>Rigolet M., DNA Res. 5:309-313(1998).<br>Pagliuca A., Genomics 27:200-203(1995).<br>Mungall A.J., Nature 425:805-811(2003).

Synonyms

DNA-binding protein inhibitor ID-4; Class B basic helix-loop-helix protein 27; bHLHb27; Inhibitor of DNA binding 4; Inhibitor of differentiation 4; ID4; BHLHB27

Gene Name

ID4

UniProt

P47928

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human ID4.

Clonality

Polyclonal

Applications

WB

Field of Research

Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Nuclear, Signaling Pathways, Stem Cells, TGF Beta, Transcription

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation (By similarity) . .

Molecular Weight

16622 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03975

Product MSDS

https://www.bosterbio.com/msds?sku=A03975

Other Gene Names

DNA-binding protein inhibitor ID-4

Subcellular Location

Nucleus.

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