Anti-UBE2D2/Ubch5B Antibody
Boster Bio Anti-UBE2D2/Ubch5B Antibody catalog # A03971-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Ubiquitin-conjugating enzyme E2 D2;2.3.2.23 ; (E3-independent) E2 ubiquitin-conjugating enzyme D2;2.3.2.24 ; E2 ubiquitin-conjugating enzyme D2; Ubiquitin carrier protein D2; Ubiquitin-conjugating enzyme E2 (17) KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; Ubiquitin-protein ligase D2; p53-regulated ubiquitin-conjugating enzyme 1; UBE2D2; PUBC1, UBC4, UBC5B, UBCH4, UBCH5B
Gene Name
UBE2D2
UniProt
P62837
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human UBE2D2. AA range:98-147
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3. .
Molecular Weight
16735 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A03971-1
Product MSDS
https://www.bosterbio.com/msds?sku=A03971-1
Fragment
IgG
Other Gene Names
Ubiquitin-conjugating enzyme E2 D2
Curated Selection
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