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Anti-Mnk1 (Ab-385) MKNK1 Antibody

Boster Bio Anti-Mnk1 (Ab-385) MKNK1 Antibody (Catalog # A03783) . Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.<br><br>Fukunaga R., EMBO J. 16:1921-1933(1997).<br>Knauf U., Mol. Cell. Biol. 21:5500-5511(2001).<br>O'Loghlen A., Exp. Cell Res. 299:343-355(2004).

Synonyms

MAP kinase-interacting serine/threonine-protein kinase 1;2.7.11.1; MAP kinase signal-integrating kinase 1; MAPK signal-integrating kinase 1; Mnk1; MKNK1; MNK1

Gene Name

MKNK1

UniProt

Q9BUB5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized non-phosphopeptide derived from human Mnk1 around the phosphorylation site of threonine 385 (L-P-T (p) -P-Q) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. .

Applications

WB

Field of Research

MAPK Pathway, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap. .

Molecular Weight

51342 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03783

Product MSDS

https://www.bosterbio.com/msds?sku=A03783

Other Gene Names

MAP kinase-interacting serine/threonine-protein kinase 1

Subcellular Location

Isoform 2: Cytoplasm.

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