Anti-PLC-g2 (Ab-1217) Antibody
Boster Bio Anti-PLC-g2 (Ab-1217) Antibody (Catalog # A03572) . Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
<br><br>Singer, W. D. et al. (1997) Annu. Rev. Biochem. 66, 475-509.
<br>Smrcka, A. V. et al. (1991) Science 251, 804-807.
<br>Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225.
<br>Watanabe, D. et al. (2001) J. Biol. Chem. 276, 38595-38601.
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Synonyms
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2;3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2; PLCG2
Gene Name
PLCG2
UniProt
P16885
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.1215~1219 (F-L-Y-D-T) derived from Human PLCg2.
Clonality
Polyclonal
Applications
IHC, IF
Field of Research
Lipid Metabolism, Lipid Signaling, Metabolism, Signal Transduction, Signaling Pathway
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/ml
Form
Liquid
Function
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Molecular Weight
147870 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A03572
Product MSDS
https://www.bosterbio.com/msds?sku=A03572
Other Gene Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
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