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Anti-Spi-B Antibody

Boster Bio Anti-Spi-B Antibody (Catalog# A02805) . Tested in IHC, WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Transcription factor Spi-B; SPIB

Gene Name

SPIB

UniProt

Q01892

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant Spi-B protein (amino acids 50-260)

Clonality

Polyclonal

Tissue Specificity

Expressed in plasmacytoid dendritic cells (pDCs) and B-cells, not expressed in T-cells or granulocytes. May also be enriched in stem cell populations of the liver.

Applications

IHC, WB

Field of Research

Epigenetics and Nuclear Signaling, Pol II Transcription, Polymerase Associated Factors, Transcription, Transcription Factors

Purification

Protein A Chromatography

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN) -producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation. .

Molecular Weight

28819 MW

Shipping Conditions

Available

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02805

Product MSDS

https://www.bosterbio.com/msds?sku=A02805

Fragment

Rabbit IgG

Other Gene Names

Transcription factor Spi-B

Subcellular Location

Isoform 1: Nucleus.

Protein Name

Transcription factor Spi-B

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