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Anti-Nkx-3.1 Monoclonal Antibody

Boster Bio Anti-Nkx-3.1 Monoclonal Antibody catalog # A02709. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Homeobox protein Nkx-3.1; Homeobox protein NK-3 homolog A; NKX3-1; NKX3.1, NKX3A

Gene Name

NKX3-1

UniProt

Q99801

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of human Nkx-3.1 expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 4H4

Tissue Specificity

Highly expressed in the prostate and, at a lower level, in the testis. .

Applications

ELISA, Flow Cytometry, IHC, WB

Purification

The antibody was isolated from ascitic fluid by immunoaffinity chromatography using antigens coupled to agarose beads.

Form

Liquid

Function

Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. .

Molecular Weight

26350 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02709

Product MSDS

https://www.bosterbio.com/msds?sku=A02709

Fragment

IgG2b

Other Gene Names

Homeobox protein Nkx-3.1

Subcellular Location

Nucleus .

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