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Anti-PEG3 Antibody

Boster Bio Anti-PEG3 Antibody (Catalog # A02541) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B By similarity. Possesses a tumor suppressing activity in glioma cells.<br><br>Van den Veyver I.B., J. Soc. Gynecol. Invest. 8:305-313(2001).<br>Kohda T., Genes Cells 6:237-247(2001).<br>Hiby S.E., Hum. Mol. Genet. 10:1093-1100(2001).

Synonyms

Paternally-expressed gene 3 protein; Zinc finger and SCAN domain-containing protein 24; PEG3; KIAA0287, ZSCAN24

Gene Name

PEG3

UniProt

Q9GZU2

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human PEG3.

Clonality

Polyclonal

Tissue Specificity

Brain, glial cells, astrocytes, embryo, placenta, testis, ovary and uterus. In the placenta it is found in the layer of villous cytotrophoblast cells while in the ovary it is found in the cells of the ovarian stroma including the thecal layers around the follicles. Expression is highly repressed in glioma cell lines. .

Applications

WB

Field of Research

Apoptosis, Associated Proteins, Cancer, Cancer Susceptibility, Cell Biology, Cell Type Marker, Domain Families, Epigenetics and Nuclear Signaling, Intracellular, Metabolism, Neurology Process, Neuron Marker, Neuroscience, Transcription, Tumor Suppressors, Zinc Finger

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity) . Possesses a tumor suppressing activity in glioma cells. .

Molecular Weight

180827 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02541

Product MSDS

https://www.bosterbio.com/msds?sku=A02541

Other Gene Names

Paternally-expressed gene 3 protein

Subcellular Location

Nucleus . Cytoplasm .

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