Anti-LEDGF PSIP1 Monoclonal Antibody
Boster Bio Anti-LEDGF PSIP1 Monoclonal Antibody catalog # A01960. Tested in IF, IHC, WB applications. This antibody reacts with Human, Monkey, Rat.
Product Specifications
Synonyms
PC4 and SFRS1-interacting protein; CLL-associated antigen KW-7; Dense fine speckles 70 kDa protein; DFS 70; Lens epithelium-derived growth factor; Transcriptional coactivator p75/p52; PSIP1; DFS70, LEDGF, PSIP2
Gene Name
PSIP1
UniProt
O75475
Host
Mouse
Reactivity
Human, Rat, Monkey
Immunogen
Purified recombinant fragment of human LEDGF expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 11168
Tissue Specificity
Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions. .
Applications
WB, IHC, IF
Purification
Ascitic fluid
Form
Liquid
Function
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. .
Molecular Weight
60103 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A01960
Product MSDS
https://www.bosterbio.com/msds?sku=A01960
Other Gene Names
PC4 and SFRS1-interacting protein
Subcellular Location
Nucleus . Remains chromatin-associated throughout the cell cycle.
Curated Selection
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