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Anti-TRI18 MID1 Antibody

Boster Bio Anti-TRI18 MID1 Antibody (Catalog # A01774) . Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.<br><br>Quaderi N.A., Nat. Genet. 17:285-291(1997).<br>Perry J., Hum. Mol. Genet. 7:299-305(1998).<br>Van den Veyver I.B., Genomics 51:251-261(1998).<

Synonyms

E3 ubiquitin-protein ligase Midline-1;6.3.2.-; Midin; Putative transcription factor XPRF; RING finger protein 59; RING finger protein Midline-1; Tripartite motif-containing protein 18; MID1; FXY, RNF59, TRIM18, XPRF

Gene Name

MID1

UniProt

O15344

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human TRI18.

Clonality

Polyclonal

Tissue Specificity

In the fetus, highest expression found in kidney, followed by brain and lung. Expressed at low levels in fetal liver. In the adult, most abundant in heart, placenta and brain.

Applications

WB, IHC, IF

Field of Research

Cell Biology, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ring Finger E3 Ligase, Ubiquitin E3 Enzymes

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. .

Molecular Weight

75251 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01774

Product MSDS

https://www.bosterbio.com/msds?sku=A01774

Other Gene Names

E3 ubiquitin-protein ligase Midline-1

Subcellular Location

Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Microtubule-associated. It is associated with microtubules throughout the cell cycle, co-localizing with cytoplasmic fibers in interphase and with the mitotic spindle and midbodies during mitosis and cytokinesis.
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