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Anti-ERCC5/Xpg Antibody

Boster Bio Anti-ERCC5/Xpg Antibody (Catalog # A01770) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.<br> <br> Scherly D., Nature 363:182-185(1993).<br> Shiomi T., Mutat. Res. 314:167-175(1994).<br> Macinnes M.A., Mol. Cell. Biol. 13:6393-6402(1993).

Synonyms

DNA repair protein complementing XP-G cells;3.1.-.-; DNA excision repair protein ERCC-5; Xeroderma pigmentosum group G-complementing protein; ERCC5; ERCM2, XPG, XPGC

Gene Name

ERCC5

UniProt

P28715

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human ERCC5.

Clonality

Polyclonal

Applications

WB

Field of Research

DNA/RNA, DNA Damage & Repair, Epigenetics and Nuclear Signaling

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER) . Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.

Molecular Weight

133108 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01770

Product MSDS

https://www.bosterbio.com/msds?sku=A01770

Other Gene Names

DNA repair protein complementing XP-G cells

Subcellular Location

Nucleus .

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