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Anti-LC3a MAP1LC3A Antibody

Boster Bio Anti-LC3a MAP1LC3A Antibody (Catalog # A01543) . Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Probably involved in formation of autophagosomal vacuoles (autophagosomes) .

Synonyms

Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B LC3 A; Microtubule-associated protein 1 light chain 3 alpha; MAP1LC3A

Gene Name

MAP1LC3A

UniProt

Q9H492

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around aa.5~10 (R-P-F-K-Q) derived from Human LC3A.

Clonality

Polyclonal

Tissue Specificity

Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes. .

Applications

WB, IF

Field of Research

Cancer, Cardiovascular, Cell Death, Cytoskeleton, Cytoskeleton/ECM, Metabolism, Metabolism Processes, Microtubules, Pathways and Processes, Signal Transduction

Purification

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/ml

Form

Liquid

Function

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141) . Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600) . .

Molecular Weight

14272 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01543

Product MSDS

https://www.bosterbio.com/msds?sku=A01543

Other Gene Names

Microtubule-associated proteins 1A/1B light chain 3A

Subcellular Location

Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome . LC3-II binds to the autophagic membranes.
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