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Anti-Endostatin COL18A1 Antibody

Boster Bio Anti-Endostatin COL18A1 Antibody (Catalog # A01302) . Tested in IHC applications. This antibody reacts with Human.

Product Specifications

Background

COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.<br><br>Takayuki Furumatsu, J. Biochem. (Tokyo), Apr 2002; 131: 619 - 626.<br>Sonja Stahl, Genes Cells, Sep 2005; 10: 929 - 939.<br>NICOLAI MIOSGE, FASEB J, Oct 1999; 13: 1743.<br>Nicholas J. MacDonald, J. Biol. Chem., Jun 2001; 276: 25190 - 25196.

Synonyms

Collagen alpha-1 (XVIII) chain; Endostatin; COL18A1

Gene Name

COL18A1

UniProt

P39060

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from human endostatin.

Clonality

Polyclonal

Tissue Specificity

Present in multiple organs with highest levels in liver, lung and kidney.

Applications

IHC

Field of Research

Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Immunohistochemistry: 1:50~1:100

Form

Liquid

Function

COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.

Molecular Weight

178188 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01302

Product MSDS

https://www.bosterbio.com/msds?sku=A01302

Other Gene Names

Collagen alpha-1 (XVIII) chain

Subcellular Location

Secreted, extracellular space, extracellular matrix .

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