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Anti-SCN4A Antibody

Boster Bio Anti-SCN4A Antibody (Catalog # A01138) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.<br><br>George A.L. Jr., Ann. Neurol. 31:131-137(1992).<br>Wang J., Biochem. Biophys. Res. Commun. 182:794-801(1992).<br>Tsujino A., Proc. Natl. Acad. Sci. U.S.A. 100:7377-7382(2003).

Synonyms

Sodium channel protein type 4 subunit alpha; SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4; SCN4A

Gene Name

SCN4A

UniProt

P35499

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human SCN4A.

Clonality

Polyclonal

Applications

WB

Field of Research

Neuroscience, Neurotransmission, Receptors / Channels

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na (+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle. .

Molecular Weight

208061 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01138

Product MSDS

https://www.bosterbio.com/msds?sku=A01138

Other Gene Names

Sodium channel protein type 4 subunit alpha

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

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