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Anti-CD209/Dc Sign Antibody

Boster Bio Anti-CD209/Dc Sign Antibody catalog # A01025-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

CD209 antigen; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1; CD209; CD209; CLEC4L

Gene Name

CD209

UniProt

Q9NNX6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from CD209 antigen at AA range: 261-310

Tissue Specificity

Predominantly expressed in dendritic cells and in DC-residing tissues. Also found in placental macrophages, endothelial cells of placental vascular channels, peripheral blood mononuclear cells, and THP-1 monocytes. .

Applications

WB

Purification

Immunogen affinity purified

Form

Liquid

Function

Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. .

Molecular Weight

45775 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01025-1

Product MSDS

https://www.bosterbio.com/msds?sku=A01025-1

Fragment

IgG

Other Gene Names

CD209 antigen

Subcellular Location

Isoform 1: Cell membrane ; Single-pass type II membrane protein .

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