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Anti-VAV1 (Ab-174) Antibody

Boster Bio Anti-VAV1 (Ab-174) Antibody (Catalog # A00691) . Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Background

Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.<br><br>Ana V. Miletic, J. Biol. Chem., Dec 2006; 281: 38257 - 38265.<br>Christopher C. Stebbins, Mol. Cell. Biol., Sep 2003; 23: 6291 - 6299.<br>Vered Schapira, Cancer Res., Jun 2006; 66: 6183 - 6191.<br>Maya Groysman, J. Biol. Chem., Dec 2002; 277: 50121 - 50130.

Synonyms

Proto-oncogene vav; VAV1; VAV

Gene Name

VAV1

UniProt

P15498

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed in hematopoietic cells but not in other cell types.

Applications

WB, IHC

Field of Research

Proto-Oncogenes, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins, Transcription

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.

Molecular Weight

98314 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00691

Product MSDS

https://www.bosterbio.com/msds?sku=A00691

Other Gene Names

Proto-oncogene vav

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