Anti-SRY Antibody
Boster Bio Anti-SRY Antibody catalog # A00614. Tested in IHC, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Sex-determining region Y protein; Testis-determining factor; SRY; TDF
Gene Name
SRY
UniProt
Q05066
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human SRY.
Clonality
Polyclonal
Applications
WB, IHC
Purification
Immunogen affinity purified
Form
Liquid
Function
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity) . In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity) . Involved in different aspects of gene regulation including promoter activation or repression (By similarity) . Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. .
Molecular Weight
23884 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A00614
Product MSDS
https://www.bosterbio.com/msds?sku=A00614
Fragment
IgG
Other Gene Names
Sex-determining region Y protein
Subcellular Location
Nucleus speckle. Cytoplasm. Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus. Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH) (By similarity) . .
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