Anti-MIP-1 alpha CCL3 Antibody
Boster Bio Anti-MIP-1 alpha CCL3 Antibody (Catalog # A00405) . Tested in WB applications. This antibody reacts with Mouse.
Product Specifications
Background
Mouse MIP-1α, or Ccl3, of the intercrine beta (chemokine CC family) is a secreted cytokine with inflammatory, pyrogenic and chemokinetic properties. It is expressed in lung, spleen, and pancreas, and has a potent chemotactic activity for eosinophils. Ccl3 binding to a high-affinity receptor activates calcium release in neutrophils.
Synonyms
MIP-1α, MIP-1 alpha, Mouse Macrophage Inflammatory Protein-1-alpha, Ccl3 cytokine, C-C motif chemokine 3, Small-inducible cytokine A3, Macrophage inflammatory protein 1-α, MIP-1-alpha, TY-5, SIS-alpha, Heparin-binding chemotaxis protein, L2G25B, Scya3 protein
Gene Name
CCL3
UniProt
P10855
Host
Rabbit
Reactivity
Mouse
Immunogen
This IgG fraction antibody was prepared from rabbit antiserum after repeated immunizations with recombinant truncated mouse MIP-1α protein produced in E.coli.
Clonality
Polyclonal
Applications
WB
Field of Research
Antiviral Signaling, Chemokines, Immune System Diseases, Immunology, Innate Immunity, Macrophage/Inflammation
Purification
This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for mouse MIP-1α protein. Cross-reactivity with MIP-1α from other sources has not been determined.
Concentration
1.0 mg/mL by UV absorbance at 280 nm
Form
Lyophilized
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Molecular Weight
10085 MW
Shipping Conditions
Available
Storage Conditions
Store vial at 4°C prior to restoration. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is six (6) months from date of opening.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A00405
Product MSDS
https://www.bosterbio.com/msds?sku=A00405
Fragment
IgG
Applications Notes
This purified antibody has been tested in western blotting and is suitable in ELISA. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 7-8 kDa in size corresponding to the mature 92 amino acid mouse MIP-1α/Ccl3 protein by western blotting in appropriate cell lysate or extract.
Other Gene Names
C-C motif chemokine
Subcellular Location
Secreted.
Curated Selection
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