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Anti-Tyrosinase Antibody

Boster Bio Anti-Tyrosinase Antibody (Catalog # A00326) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5, 6-dihydroxyindole to indole-5, 6 quinone.<br><br>Patricia Giraldo, Nucleic Acids Res., Nov 2003; 31: 6290 - 6305. <br>R Halaban, J. Cell Biol., Aug 1983; 97: 480. <br>Hee-Young Park, J. Biol. Chem., Jun 1999; 274: 16470. <br>BB Fuller, J. Biol. Chem., Mar 1987; 262: 4024 - 4033.

Synonyms

Tyrosinase;1.14.18.1; LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen AB; TYR

Gene Name

TYR

UniProt

P14679

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from Internal of human tyrosinase.

Clonality

Polyclonal

Applications

WB

Field of Research

Amino Acid Metabolism, Amino Acids, Cancer, Intracellular Signaling, Metabolic Signaling Pathways, Metabolism, Neuroscience, Neurotransmission, Pathways and Processes, Protein Phosphorylation, Signal Transduction, Tyrosine Phosphatases

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.

Molecular Weight

60393 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00326

Product MSDS

https://www.bosterbio.com/msds?sku=A00326

Other Gene Names

Tyrosinase

Subcellular Location

Melanosome membrane ; Single-pass type I membrane protein .

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