Anti-IRS-1 (Ab-636) Antibody
Boster Bio Anti-IRS-1 (Ab-636) Antibody (Catalog # A00268) . Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit
<br><br>Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98(8): 4640-4645
<br>Tzatsos A, et al. (2006) Mol Cell Biol; 26(1): 63-76
<br>Kadowaki T, et al. (2000) J Clin Invest; 106(4): 459-465
<br>Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98(8): 4640-4645
<br>Szanto I, et al. (2000) Proc Natl Acad Sci U S A; 97(5): 2355-2360
Gene Name
IRS1
UniProt
P35568
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.634~638 (P-M-S-P-K) derived from Human IRS-1.
Clonality
Polyclonal
Applications
WB, IHC, IF
Field of Research
Adapters, Atherosclerosis, Cancer, Cardiovascular, Cell Type Markers, Cytoplasmic, Diabetes, Diabetes-associated, Growth Factors/Hormones, Heart Disease, Metabolism, Neurology Process, Neuroscience, Obesity, Signal Transduction, Tags & Cell Markers, Tumor Associated
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/ml
Form
Liquid
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A00268
Product MSDS
https://www.bosterbio.com/msds?sku=A00268
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