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Human soluble CD6 PicoKine® Quick ELISA Kit

Human soluble CD6 PicoKine® Quick ELISA Kit (90 minutes, 96 Tests) . Quantitate Human CD6 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA) . Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

CD6 (Cluster of Differentiation 6) is a human protein encoded by the CD6 gene. It is mapped to 11q12.2. CD6 is expressed predominantly in peripheral T cells and mature medullary thymocytes. This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. What's more, this gene may be associated with susceptibility to multiple sclerosis.

Synonyms

T-cell differentiation antigen CD6; T12; TP120; CD6; CD6

Gene Name

T-cell differentiation antigen CD6

UniProt

P30203

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: H18-E398

Tissue Specificity

Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.

Applications

ELISA

Sample Type

Cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA) .

Detection Range

156 pg/ml - 10,000 pg/ml

Sensitivity

<10 pg/ml

Function

Involved in cell adhesion. Binds to CD166.

Storage Conditions

Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Product Datasheet

https://www.bosterbio.com/datasheet?sku=FEK1221

Product MSDS

https://www.bosterbio.com/msds?sku=FEK1221

Other Gene Names

CD6

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Protein Name

T-cell differentiation antigen CD6

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