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Human DNER ELISA Kit PicoKine®

Human DNER ELISA Kit PicoKine® (96 Tests) . Quantitate Human DNER in cell culture supernatants, serum and plasma (heparin, EDTA, citrate) . Sensitivity: 30pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Delta and Notch-like epidermal growth factor-related receptor is a protein that in humans is encoded by the DNER gene. It is mapped to 2q36.3. DNER, also known as BET, is a type I transmembrane glycoprotein that is specifically expressed on nonaxonal areas of post-mitotic neurons. The protein has an extracellular domain containing ten distinct EGF-like repeats similar to those found on Delta and Notch. Human and mouse DNER share 90% amino acid sequence identity.

Synonyms

Delta and Notch-like epidermal growth factor-related receptor; DNER; BET; UNQ262; PRO299

Gene Name

Delta/notch like EGF repeat containing

UniProt

Q8NFT8

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: N35-Y640

Tissue Specificity

Expressed in brain, spinal cord and adrenal gland.

Applications

ELISA

Sample Type

Cell culture supernatants, serum and plasma (heparin, EDTA, citrate) .

Detection Range

62.5 pg/ml - 4,000 pg/ml

Sensitivity

<30 pg/ml

Function

Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Storage Conditions

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EK2080

Product MSDS

https://www.bosterbio.com/msds?sku=EK2080

Other Gene Names

DNER

Subcellular Location

Cell membrane. Single-pass type I membrane protein.

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