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Human SLITRK1 ELISA Kit PicoKine®

Human SLITRK1 ELISA Kit PicoKine® (96 Tests) . Quantitate Human SLITRK1 in cell culture supernatants, serum and plasma (heparin) . Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

SLIT and NTRK-like protein 1 is a protein that in humans is encoded by the SLITRK1 gene. It is mapped to 13q31.1. This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. However, the protein encoded by this gene lacks the region of homology to neurotrophin receptors. This protein is thought to be involved in neurite outgrowth. Mutations in this gene may be associated with Tourette syndrome. Alternative splicing results in multiple transcript variants.

Synonyms

SLIT and NTRK-like protein 1; Leucine-rich repeat-containing protein 12; SLITRK1; KIAA1910; LRRC12; UNQ233; PRO266

Gene Name

SLIT and NTRK like family member 1

UniProt

Q96PX8

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: N18-P622

Tissue Specificity

Expressed predominantly in the frontal lobe of the cerebral cortex of the brain. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.

Applications

ELISA

Sample Type

Cell culture supernatants, serum and plasma (heparin) .

Detection Range

31.2 pg/ml - 2,000 pg/ml

Sensitivity

<10 pg/ml

Function

It is involved in synaptogenesis and promotes excitatory synapse differentiation. Enhances neuronal dendrite outgrowth.

Storage Conditions

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EK1866

Product MSDS

https://www.bosterbio.com/msds?sku=EK1866

Other Gene Names

SLITRK1

Subcellular Location

Secreted. Membrane. Single-pass type I membrane protein. Synapse.

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