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Rat JAM-C ELISA Kit PicoKine®

Rat JAM-C ELISA Kit PicoKine® (96 Tests) . Quantitate Rat Jam3 in cell culture supernatants, serum and plasma (heparin, EDTA) . Sensitivity: 5pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

JAM3 belongs to the junctional adhesion molecule protein family and functions as a receptor for another member of this family. This gene is mapped to 8q13. JAM3 plays a part in cell-cell adhesion. The soluble form of JAM3 is a mediator of angiogenesis. JAM3 is a counter-receptor for ITGAM, mediating leukocyteplatelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN) . A mutation in an intron of the JAM3 gene is linked with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts.

Synonyms

Junctional adhesion molecule C; JAM-C; Junctional adhesion molecule 3; JAM-3; Jam3

Gene Name

Junctional adhesion molecule 3

UniProt

Q68FQ2

Reactivity

Rat

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: V32-N241

Applications

ELISA

Field of Research

Atherosclerosis, Cardiovascular, Cell Adhesion, Cell Adhesion Molecules, Cell Type Markers, Cytoskeleton/ECM, Platelets, Signal Transduction, Tags & Cell Markers, Vascular Inflammation, Vasculature

Sample Type

Cell culture supernatants, serum and plasma (heparin, EDTA) .

Detection Range

15.6 pg/ml - 1,000 pg/ml

Sensitivity

<5 pg/ml

Function

May participate in cell-cell adhesion distinct from tight junctions.

Storage Conditions

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EK1841

Product MSDS

https://www.bosterbio.com/msds?sku=EK1841

Other Gene Names

Jam3

Subcellular Location

Extracellular space, Cell membrane, Single-pass type I membrane protein, desmosome

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