Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human IL-23R/Interleukin-23 receptor ELISA Kit PicoKine®

Human IL-23R ELISA Kit PicoKine® (96 Tests) . Quantitate Human IL23R in cell culture supernatants, serum and plasma (heparin, EDTA) . Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

Synonyms

Interleukin-23 receptor; IL-23 receptor; IL-23R; IL23R

Gene Name

Interleukin 23 receptor

UniProt

Q5VWK5

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: I25-I354

Tissue Specificity

Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells.

Applications

ELISA

Field of Research

Cell Type Markers, Cytokines, Epigenetics and Nuclear Signaling, Immunoglobulins, Immunology, Innate Immunity, Interleukins, Nuclear Signaling, Nuclear Signaling Pathways, Receptors, Signal Transduction, Signaling Pathway

Sample Type

Cell culture supernatants, serum and plasma (heparin, EDTA) .

Detection Range

156 pg/ml - 10,000 pg/ml

Sensitivity

<10 pg/ml

Function

Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

Storage Conditions

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EK1612

Product MSDS

https://www.bosterbio.com/msds?sku=EK1612

Other Gene Names

IL23R

Subcellular Location

Cell membrane

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

HSP27 (phospho Ser82) Polyclonal Antibody
MBS8519910-01 0.1 mg

HSP27 (phospho Ser82) Polyclonal Antibody

Ask
View Details
HSP27 (phospho Ser82) Polyclonal Antibody
MBS8519910-02 0.1 mL (AF635)

HSP27 (phospho Ser82) Polyclonal Antibody

Ask
View Details
HSP27 (phospho Ser82) Polyclonal Antibody
MBS8519910-03 0.1 mL (AF610)

HSP27 (phospho Ser82) Polyclonal Antibody

Ask
View Details
HSP27 (phospho Ser82) Polyclonal Antibody
MBS8519910-04 0.1 mL (AF405S)

HSP27 (phospho Ser82) Polyclonal Antibody

Ask
View Details
HSP27 (phospho Ser82) Polyclonal Antibody
MBS8519910-05 0.1 mL (AF405L)

HSP27 (phospho Ser82) Polyclonal Antibody

Ask
View Details
HSP27 (phospho Ser82) Polyclonal Antibody
MBS8519910-06 0.1 mL (AF546)

HSP27 (phospho Ser82) Polyclonal Antibody

Ask
View Details