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Human beta IG-H3/TGFBI ELISA Kit PicoKine®

Human beta IG-H3/TGFBI ELISA Kit PicoKine® (96 Tests) . Quantitate Human TGFBI in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA) . Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Transforming growth factor, beta-induced, 68kDa, also known as TGFBI (initially called BIGH3, BIG-H3), is a protein which in humans is encoded by the TGFBI gene. It is mapped to 5q31.1. This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion.

Synonyms

Transforming growth factor-beta-induced protein ig-h3; Beta ig-h3; Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP; TGFBI; BIGH3

Gene Name

Transforming growth factor-beta-induced protein ig-h3

UniProt

Q15582

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: G24-H683

Tissue Specificity

Highly expressed in the corneal epithelium. .

Applications

ELISA

Field of Research

Collagen, Cytoskeleton/ECM, Developmental Biology, ECM Proteins, Extracellular Matrix, Growth Factors/Hormones, Neuroscience, Organogenesis, Sensory System, Signal Transduction, Structures, Visual System

Sample Type

Cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA) .

Detection Range

62.5 pg/ml - 4,000 pg/ml

Sensitivity

<10 pg/ml

Function

Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation.

Storage Conditions

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EK1202

Product MSDS

https://www.bosterbio.com/msds?sku=EK1202

Other Gene Names

TGFBI

Subcellular Location

Secreted, extracellular space, extracellular matrix. May be associated both with microfibrils and with the cell surface.

Sequence Similarities

Contains 1 EMI domain.

Protein Name

Transforming growth factor-beta-induced protein ig-h3

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