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Human Betacellulin/BTC ELISA Kit PicoKine®

Human Betacellulin/BTC ELISA Kit PicoKine® (96 Tests) . Quantitate Human BTC in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA) . Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Betacellulin, also known as BTC is a protein that in humans is encoded by the BTC gene. This gene is mapped to 4q13.3. The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. It is the growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. This protein is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.

Synonyms

Probetacellulin; Betacellulin; BTC; BTC

Gene Name

Probetacellulin

UniProt

P35070

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: E.coli; Immunogen sequence: D32-Y111

Tissue Specificity

Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. .

Applications

ELISA

Field of Research

Cancer, Growth Factors, Growth Factors/Hormones, Signal Transduction

Sample Type

Cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA) .

Detection Range

15.6 pg/ml - 1,000 pg/ml

Sensitivity

<10 pg/ml

Function

Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. .

Storage Conditions

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EK0980

Product MSDS

https://www.bosterbio.com/msds?sku=EK0980

Other Gene Names

BTC

Subcellular Location

Betacellulin: Secreted, extracellular space.

Protein Name

Probetacellulin

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