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Mouse HAI-2/SPINT2 ELISA Kit PicoKine®

Mouse HAI-2/SPINT2 ELISA Kit PicoKine® (96 Tests) . Quantitate Mouse Spint2 in cell culture supernatants, serum, plasma (heparin, EDTA) and cell lysates. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Kunitz-type protease inhibitor 2 is an enzyme inhibitor that in humans is encoded by the SPINT2 gene. This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. And this gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

Kunitz-type protease inhibitor 2; Hepatocyte growth factor activator inhibitor type 2; HAI-2; Spint2; Hai2

Gene Name

Kunitz-type protease inhibitor 2

UniProt

Q9WU03

Reactivity

Mouse

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: R30-K140

Tissue Specificity

Isoform 2 is more predominantly expressed than isoform 1.

Applications

ELISA

Field of Research

Cell Biology, Developmental Biology, Neurogenesis, Neurology Process, Neuroscience, Protease Inhibitors, Proteolysis/Ubiquitin, Reproduction

Sample Type

Cell culture supernatants, serum, plasma (heparin, EDTA) and cell lysates.

Detection Range

31.2 pg/ml - 2,000 pg/ml

Sensitivity

<10 pg/ml

Function

Inhibitor of HGF activator.

Storage Conditions

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EK0774

Product MSDS

https://www.bosterbio.com/msds?sku=EK0774

Other Gene Names

Spint2

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Protein Name

Kunitz-type protease inhibitor 2

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