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Mouse Neurotrophin-3 ELISA Kit PicoKine®

Mouse Neurotrophin-3 ELISA Kit PicoKine® (96 Tests) . Quantitate Mouse Ntf3 in cell culture supernatants and serum. Sensitivity: 2pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Neurotrophin-3 (NT-3) is a new member of the nerve growth factor gene family, which plays an important role in the development and maintenance of the vertebrate nervous system.NT-3 and its receptor, called neurotrophic tyrosine kinase receptor type 3 (Ntrk3; also called TrkC), are expressed early and throughout embryogenesis. NT-3 is one of five neurotrophin growth factors which shape the development of the nervous system by regulating neuronal survival and differentiation. NT-3 may be one of the central nervous system-derived factors that mediate neural crest (NC) cell proliferation in vivo. NT-3 has been mapped to human chromosome 12p and mouse chromosome 6.

Synonyms

Neurotrophin-3; NT-3; HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factor; Ntf3; Ntf-3

Gene Name

Neurotrophin-3

UniProt

P20181

Reactivity

Mouse

Cross Reactivity

There is cross-reactivity with NT-4<2.5%, and no detectable cross-reactivity with any other cytokine.

Immunogen

Expression system for standard: NS0; Immunogen sequence: Y139-T257

Tissue Specificity

Brain and peripheral tissues.

Applications

ELISA

Field of Research

Growth and Development, Neurology Process, Neuroscience

Sample Type

Cell culture supernatants and serum.

Detection Range

15.6 pg/ml - 1,000 pg/ml

Sensitivity

<2 pg/ml

Function

Seems to promote the survival of visceral and proprioceptive sensory neurons.

Storage Conditions

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EK0473

Product MSDS

https://www.bosterbio.com/msds?sku=EK0473

Other Gene Names

NTF3

Subcellular Location

Secreted.

Protein Name

Neurotrophin-3

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