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Anti-Human CD11b DyLight® 550 conjugated ITGAM Antibody

Boster Bio Anti-Human CD11b DyLight® 550 conjugated ITGAM Antibody catalog # A00144-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b; ITGAM; CD11B; CR3A

Gene Name

Integrin alpha M

UniProt

P11215

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human CD11b recombinant protein (Position: N129-E336) .

Clonality

Polyclonal

Conjugation

DyLight®550

Tissue Specificity

Predominantly expressed in monocytes and granulocytes.

Applications

Flow Cytometry

Field of Research

Cell Adhesion, Cell Type Marker, Cell Type Markers, Cytoskeleton/ECM, Hematopoietic Progenitors, Integrins, Lymphoid, Mesenchymal Stem Cells, Myeloid, Neuroscience, Signal Transduction, Stem Cells, T Lymphocytic Lineage

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Storage Conditions

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00144-Dyl550

Product MSDS

https://www.bosterbio.com/msds?sku=A00144-Dyl550

Fragment

Rabbit IgG

Applications Notes

6

Other Gene Names

ITGAM

Subcellular Location

Membrane; Single-pass type I membrane protein.

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